UNVEILING CHALLENGES IN REAL-TIME PCR STRATEGIES FOR DETECTING TREATMENT FAILURE: OBSERVATIONS FROM CLINICAL TRIALS ON CHRONIC CHAGAS DISEASE

Unveiling challenges in real-time PCR strategies for detecting treatment failure: observations from clinical trials on chronic Chagas disease

Chagas disease (CD) caused by Trypanosoma cruzi remains a Neglected Tropical Disease with limited access to diagnosis and treatment, particularly for chronically infected patients.Clinical trials are underway to improve treatment using new drugs or different regimens, and Real-Time PCR is used to assess the parasitological response as a surrogate b

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Ethylene represses the promoting influence of cytokinin on cell division and expansion of cotyledons in etiolated Arabidopsis thaliana seedlings

The plant hormones ethylene and cytokinin influence many processes; sometimes they act cooperatively, other times antagonistically.To study their Inline - Wheels Court antagonistic interaction, we used the cotyledons of etiolated, intact seedlings of Arabidopsis thaliana.We focused on cell division and expansion, because both processes are quantifi

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Control of pink discoloration in coconut water

The pink discoloration in coconut water is a result of the initial enzymatic action of polyphenol oxidase (PPO) on the phenolic substrates which are naturally present in the product.Activity of the enzyme is further enhanced by metal contamination such as copper and exposure of the product to high temperature during its processing and storage.The o

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